reverse transcriptase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12715	Reverse transcriptase-IN-1		HIV Protease
	Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7 nM.		HIV Protease
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
T7447	Adefovir		HBV , Reverse Transcriptase , Telomerase
	Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor used for treatment of hepatitis B and herpes simplex virus infection.		HBV , Reverse Transcriptase , Telomerase
T72203	Reverse transcriptase-IN-3
	Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.
T12609	R-10015		LIM Kinase , Reverse Transcriptase
	R-10015 is a highly potent and selective LIMK inhibitor that blocks LIMK by binding to the ATP-binding pocket. It inhibits human LIMK1 with an IC50 value of 38 nM. It also exerts broad-spectrum antiviral effects and may ...		LIM Kinase , Reverse Transcriptase
T9223	RO-0335		Reverse Transcriptase
	RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is...		Reverse Transcriptase
T16530	BF738735		Antiviral , PI4K
	BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity.		Antiviral , PI4K
T72206	Reverse transcriptase-IN-4
	Reverse transcriptase-IN-4 is a potent, selective non-nucleoside reverse transcriptase (NNRT) inhibitor, demonstrating an EC50 of 0.053 μM against wild-type HIV-1 and 0.26 μM for the E138K HIV-1 mutant.
T16098	Islatravir	MK-8591	HIV Protease , Reverse Transcriptase
	Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively).		HIV Protease , Reverse Transcriptase
T10133	3'-Azido-3'-deoxy-5-methylcytidine		Antiviral , HIV Protease
	3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase(EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus (XMRV, CC50 = 43.5 μM).		Antiviral , HIV Protease
T2330	Rilpivirine	TMC278,R278474,DB08864	HIV Protease , Reverse Transcriptase
	Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections.		HIV Protease , Reverse Transcriptase
T6519	Gramine	NSC 16892,Donaxine	Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor
	Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als...
T3632	Doravirine	MK-1439	HIV Protease , Reverse Transcriptase
	Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.		HIV Protease , Reverse Transcriptase
T5981	2,2'-Anhydrouridine	O2,2'-Cyclouridine,2,2'-Cyclouridine	Antiviral , Reverse Transcriptase
	2,2'-Anhydrouridine (2,2'-Cyclouridine) is a research tool for antiviral and anticancer studies.		Antiviral , Reverse Transcriptase
T6214	Emtricitabine	FTC,Emtriva,BW1592	HIV Protease , Reverse Transcriptase
	Emtricitabine (FTC) (FTC), a nucleoside reverse transcriptase inhibitor, exhibits inhibition activity against human immunodeficiency virus (HIV) and hepatitis B virus.		HIV Protease , Reverse Transcriptase
T1267	Abacavir	Epzicom,Ziagen,Abacavir sulfate	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.		Apoptosis , HIV Protease , Reverse Transcriptase
T2578	Didanosine	ddI,2',3'-Dideoxyinosine	HIV Protease , Reverse Transcriptase
	Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).		HIV Protease , Reverse Transcriptase
T27154	Dexelvucitabine	D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase
	Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.		Reverse Transcriptase
T1815	Dapivirine	R147681,TMC120	Apoptosis , HIV Protease , Reverse Transcriptase , Autophagy
	Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.
T2551	Etravirine	TMC125,R165335	HIV Protease , Reverse Transcriptase
	Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribe...		HIV Protease , Reverse Transcriptase